Technologies

GREEN-CHEMICAL-COUL

Green chemistry

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FERMENTED-COUL

Fermented natural products

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PLANT-EXTRACT-COUL

Plant extracts

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NATURAL LIPIDS-COUL

Natural lipids

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SYNBIO -ACTIVE-COUL

SynBio assets

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GREEN-CHEMICAL-COUL

Green chemistry

  • Active ingredients that reproduce some of nature’s most powerful signaling molecules.
  • Each ingredient is designed to interact with the skin’s natural longevity mechanisms and restore its long-term cellular intelligence.
  • Formulated according to green chemistry principles for clean, stable and precise targeting.

Pillars of cellular longevity :

1. Repair (Millesis Pure)

2. Prolongation (Clotholine Pure)

3. Protection (Vitalisis Pure)

The right ingredients :

Millesis pure ( blue)
INCI: Caffeoyl Methoxytryptamine Repairing
  • Cellular reprogramming
  • Restructuring the extracellular matrix
  • Restoring dermal architecture

Biomimetic molecule inspired by plant alkaloids, with strong redox activity, capable of reactivating gene expression in mature cells and restoring dermal architecture.

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Clotholine Pure (blue)

INCI: Coumaroyl Methoxytryptamine Prolongation

  • Activation of the Klotho protein, associated with youthfulness
  • Regulation of senescence
  • Extended cell life

This molecule mimics cornflower’s protective indole alkaloids and acts on the cell longevity pathway by restoring Klotho protein signaling.

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Vitalisis pure ( blue)

INCI: Caffeoyl Pyridoxamine (pending) Protection

  • SIRT6 activation
  • DNA protection
  • Core resilience

Biomimetic molecule combining a polyphenol with a
human vitamin cofactor (Vit. B6), designed to preserve genomic integrity by activating cellular longevity pathways, protecting DNA from environmental aggressors and reinforcing core stability for durably resilient skin.

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FERMENTED-COUL

Fermented natural products

Platform dedicated to the transformation of natural biomolecules through precision enzymatic fermentation. Instead of extracting active ingredients and using them as they are, we let biology sublimate them for improved skin compatibility and enhanced performance.

Improved molecular bioavailability :

1. Greater stability than crude extracts

2. Higher functional concentration

3. Reduced environmental impact

4. Gentle, environmentally-friendly manufacturing process

5. Reproducible performance

The right ingredients :

Artemiline-F (white)
INCI: Artemisia capillaris extract, lactobacillus
ferment and lysate
  • Fermented Artemisia extract to improve the hair follicle microenvironment.
  • Targets key hair loss pathways: decreases 5α-reductase and DKK1 and increases VEGF to maintain Wnt signaling, which supports follicular activity.
  • Clinically proven: increased hair density in androgenic alopecia after 24 weeks.
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Collamung (white)

INCI: Phaseolus radiatus seed extract

  • Fermented mung bean extract rich in tannins, sterols and flavonoids with powerful soothing properties
  • Protects sensitive skin and strengthens the cutaneous barrier, reducing irritation while preserving skin homeostasis
  • Additional anti-aging restructuring effect, stimulating
    collagen I and restoring the architecture of dermal papillae
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Neomel-G (white)

INCI: Glycolipids

  • Ceramide-mimicking multifunctional active ingredient improves barrier function and hydration
  • Self-assembly: forming lamellar and micellar structures in emulsions and on the skin
  • Optimized formulation: higher solubility than ceramides while co-emulsifying O/W and W/O systems
  • Biological activity: soothes and supports collagen
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TwainMoist (white)

INCI: Glycerin (and) Aqua (and) Polyglutamic acid

  • Fermentation-derived PGA, combining high- and low-molecular-weight PGAs for multi-level hydration
  • Stimulates skin hydration pathways, increasing NMF and hyaluronic acid synthesis while reducing insensible water loss (IWL)
  • Clinically proven to be more effective than hyaluronic acid,
    offers plumping and anti-aging benefits.
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WinterBloom (white)
INCI: Camellia japonica flower ex-tract,
Lactobacillus ferment filtrate
  • Biofermented camellia extract from Jeju Island (Korea), which improves skin vitality and cellular communication.
  • Restores dermal-epidermal cohesion and preserves dermal fibers, for firmer, denser skin.
  • Reinforces antioxidant defenses, contributing to overall anti-aging protection.
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PLANT-EXTRACT-COUL

Plant extracts

Optimized plant extraction technologies for high concentration of active molecules or rheology.

The right ingredients :

SynerOxGuard (blue)

INCI: Camellia sinensis leaf extract, olea europaea

(olive) leaf extract, vitis vinifera (grape) fruit extract

  • Synergistic antioxidant system designed to protect skin against oxidative and environmental stress at low concentrations
  • It combines titrated and upcycled natural active ingredients
    to neutralize ROS and reinforce cellular defense mechanisms against lipid peroxidation.
  • Beyond protection, it acts as a skin resilience booster, helping to preserve the skin’s integrity and radiance over the long term.
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RheoTouch (blue)

INCI: Cellulose citrate (nano) (pending)

(and) Glycerin

  • He is the architect of new-generation natural formulations.
  • Its wood-based cellulose nanofibril provides precise texture control
    and a unique sensory profile.
  • It ensures rheofluidifying behavior, suspension and stabilization, while preserving the lightness and elegance of formulations, including transparent ones.
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NATURAL LIPIDS-COUL

Natural lipids

Collection of high-performance botanical oils, selected for their unique biochemical profiles and skin compatibility.

We focus on :

1. Geographical excellence

2. Biochemical specificity

3. Functional performance beyond the emollient effect

4. Durability and traceability

The right ingredients :

HempGlow (white)
INCI: Cannabis sativa seed oil
  • Cold-pressed in Sweden, this affordable hemp oil offers an optimal fatty acid profile that helps rebalance stressed, sensitive or acne-prone skin, restoring balance and comfort.
  • Optimal omega-3 to omega-6 ratio, rich in gamma-linolenic acid
  • Light, silky sensory texture
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LipoYouth (white)

INCI: Caryodendron orinocense seed oil

  • The cacay is a unique, sustainably cultivated tree native to the Amazon. Native to Colombia, it produces nutrient-rich nuts.
  • Its high-quality oil offers a very high concentration of biocompatible linoleic acid, squalene and vitamins. It is a powerful lipoactive for skin regeneration (renewal, elasticity, wrinkles) and hair care (repair and shine).
  • Grown according to Rainforest Alliance certification and regenerative agriculture.
  • Light to moderately oily sensation on the skin.
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MadaOpuntia (white)

INCI: Opuntia ficus-indica seed oil

  • Sourced from Madagascar, this rare oil is one of nature’s most concentrated sources of vitamin E, providing powerful antioxidant protection while promoting skin repair and barrier restoration.
  • Its unique composition includes a high concentration of tocopherols, phytosterols, linoleic acid and polyphenolic compounds.
  • Ideal for nourishing and repairing the skin
  • Rich, non-greasy texture
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SYNBIO -ACTIVE-COUL

Synbio active ingredients

Next-generation cosmetic actives created through precision bioengineering

The approach is based on :

1. Designing biological systems

2. Programming the cells of living micro-organisms

3. The production of highly-defined, pure molecules

4. Targeting specific cutaneous pathways

The right ingredients :

RegeNova-XF2 ( blue )

INCI: Aqua (and) sodium chloride (and)

dipotassium phosphate (and) monopotassium

phosphate (and) SH-polypeptide 1

  • Advanced cell regeneration signal for advanced longevity formulas.
  • Bioengineered growth factor, developed
    using synthetic biology and precision fermentation.
  • Targets key regeneration pathways to
    stimulate skin renewal and improve skin’s structural integrity.
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Boost your marketing claims
with proven active ingredients

Beyond the ingredient, we position ourselves as an extension of your R&D team. From selecting the ideal active ingredient to optimizing your formulas, we’re with you every step of the way, turning our scientific innovations into tangible commercial successes.

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